https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44998 −1, and injection volume was 10 μl. Detection was made at 254 nm by using a dual absorbance detector (DAD). The reversed-phase high-performance liquid chromatography (RP-HPLC) method has been developed and validated as per the current International Conference on Harmonization (ICH) guidelines to estimate hydroxychloroquine sulfate tablets. As part of method validation, specificity, linearity, precision, and recovery parameters were verified. The concentration and area relationships were linear (R² > 0.999) over the concentration range of 25–300 μg ml⁻¹ for hydroxychloroquine (HCQ). The relative standard deviations for precision and intermediate precision were <1.5%. The proposed RP-HPLC generic method was applied successfully to evaluate the in vitro dissolution profile with different pH conditions such as 0.1 N HCl, pH 4.5 acetate buffer, and pH 6.8 phosphate buffers as US-marketed reference products.]]> Wed 26 Oct 2022 09:23:16 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25334 Wed 11 Apr 2018 15:03:48 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53288 Tue 21 Nov 2023 10:30:38 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51603 Tue 12 Sep 2023 13:35:47 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40279 Mon 08 Aug 2022 11:55:28 AEST ]]>